Product Description

Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity.GIPR:0.0643 nM (EC50, human), GIPR:0.057 nM (Ki, human), GLP1R:0.794 nM (EC50, mouse), GIPR:2.8 nM (Ki, mouse), GCGR:5.79 nM (EC50, human), GCGR:2.32 nM (EC50, mouse), GCGR:73 nM (Ki, mouse), GLP1R:7.2 nM (Ki, human), GIPR:0.191 nM (EC50, mouse), GLP1R:1.3 nM (Ki, mouse), GCGR:5.6 nM (Ki, human), GLP1R:0.775 nM (EC50, human)