2. Physical PropertiesAppearance: White to off-white crystalline powderSolubility: Slightly soluble in water, soluble in DMSO, sparingly soluble in ethanolStorage Conditions: Store at 2-8°C (refrigerated), protected from light and moisture, in airtight containers
3. Pharmaceutical UsesIndications: Used for treating myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), and other hematological malignancies.Mechanism of Action: Inhibits DNA methyltransferase, reactivates tumor suppressor genes, and induces differentiation/apoptosis in cancer cells.Route of Administration: Typically formulated as injectable solutions (IV or subcutaneous injection).
4. Quality StandardsPharmacopoeia Compliance: USP (US), EP (EU), ChP (China), etc.Key Quality Indicators:Purity ≥99.0% (HPLC)Impurity limits, residual solvents, and heavy metals compliant with ICH guidelines
