2. Physical PropertiesAppearance: White crystalline powderSolubility: Slightly soluble in water; soluble in DMSO and alkaline solutionsStorage: Store at room temperature (20–25°C), protected from light in airtight containers
3. Pharmaceutical UsesIndications: Treatment of various solid tumors (e.g., breast, colorectal, gastric cancer) and hematological malignancies.Mechanism: Pyrimidine analog that inhibits thymidylate synthase, blocking DNA/RNA synthesis in rapidly dividing cells.Route: Oral, intravenous (IV), or topical administration (depending on formulation).
4. Quality StandardsPharmacopoeias: USP, EP, ChP, JPKey Specs:Purity ≥99.0% (HPLC)Related substances ≤0.5% (individual impurity limits)Residual solvents compliant with ICH guidelines
