Product Description

Hotgen  NT-proBNP Test Cassette

Full  name: N-terminal pro B-type natriuretic peptide

Hotgen  NT-proBNP is an accurate, rapid, semi-quantitative immunochromatografic test for  the determination of the N-terminal fragment of brain-type natriuretic peptide  in human serum, plasma and whole blood as an aiding tool for screening,  diagnosis and risk assessment of life-threatening heart failure  (HF).

NT-proBNP:  A proven biomarker for heart failure 

The N-terminal  pro B-type natriuretic peptide  (NT-proBNP) is a 76 amino  acid N-terminal inactive protein that is cleaved from proBNP to release brain  natriuretic peptide.

The  plasma concentrations of both BNP and NT-proBNP are typically increased in  patients with asymptomatic or symptomatic left ventricular dysfunction and is  associated with coronary artery disease and myocardial ischemia. As the latter  is more stable and has higher concentration and a longer shelf life in blood,  NT-proBNP is a much better biomarker and used much more  often.

Early  diagnosis of heart failure is key to improve patient outcome. Using NT-proBNP  can help clinicians optimize management of patients with dyspnea in the  emergency room. This has shown to result in significant cost savings for  healthcare structures due to shorter stays in the emergency department and  reduced patient re-hospitalization.

International  guidelines recommend the use of B-type natriuretic peptide testing in the  diagnostic workup of Heart Failure (HF) in both acute and non-acute patient  presentation.

Benefits  of NT-proBNP test in summary:

Diagnosis  of patients with suspected CHF

Risk  stratification of patients with HF

Risk  stratification of patients with ACS

Assessment  of increased risk for cardiovascular events and mortality in patients at risk  for HF who have stable CAD

Hotgen NT-proBNP  Test Principle

Colloidal  gold immunochromatographic method

Hotgen NT-proBNP  Test Features

Semi-quantitative  NT-proBNP measurement

Rapid,  accurate, lab quality results within minutes

All-inclusive  kit including reference card for value estimation

Ready-to-use  reagents

Serum,  plasma and whole blood are applicable as sample

Long  shelf life

Easy  storage at room temperature

Single  dose format: run only the test you need