Product Description

 UPTquik® Interleukin 6 (IL-6)  Kit

UPTquik®  IL-6 is an accurate, rapid, fully quantitative test used on UPTquik® Reader for  the determination of interleukin 6 (IL-6) in human serum and plasma as an aiding  tool for early diagnosis of infection.

IL-6:  An early, non-specific marker for infection

Interleukin  6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an  anti-inflammatory myokine. In humans, it is encoded by the IL6 gene.  

IL-6  is secreted by T cells and macrophages to stimulate immune response, e.g. during  infection and after trauma, especially burns or other tissue damage leading to  inflammation. IL-6 also plays a role in fighting infection, as IL-6 has been  shown in mice to be required for resistance against bacterium Streptococcus  pneumoniae.

In  addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth  muscle cells in the tunica media of many blood vessels also produce IL-6 as a  pro-inflammatory cytokine. IL-6's role as an anti-inflammatory cytokine is  mediated through its inhibitory effects on TNF-alpha and IL-1, and activation of  IL-1ra and IL-10.

Elevated  IL-6 levels may occur in different conditions including and not limited to:  chronic infections, autoimmune disorders, certain cancers, and Alzheimer’s  disease.

IL-6  test is used to help evaluate a person who has a condition associated with  inflammation, such as lupus or rheumatoid arthritis, or with infection, such as  sepsis. It may also be used in the evaluation of diabetes or cardiovascular  disease.

UPTquik® IL-6 Kit Test  Principle

Up-converting  Phosphor Technology

UPTquik® IL-6 Kit Features